In case of creatin supplementation, should it be ingested pre-training or does it not matter? This in case of benefits in MPS and such?

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Georgiy Korobeynikov

Take creatine before training is not appropriate. Metabolic processes are very inert and work on the principle of accumulation.

David Gamero del Castillo

Dear Peter,

Many studies release protocols taking pre workout creatine. I send you, two papers that could answered your question and could be the first point of a good answer and could help you to find other related papers.

Louis, M., Poortmans, J. R., Francaux, M., Hultman, E., Berré, J., Boisseau, N., ... & Waddell, T. (2003). Creatine supplementation has no effect on human muscle protein turnover at rest in the postabsorptive or fed states. American Journal of Physiology-Endocrinology and Metabolism, 284(4), E764-E770.

Antonio, J., & Ciccone, V. (2013). The effects of pre versus post workout supplementation of creatine monohydrate on body composition and strength. Journal of the International Society of Sports Nutrition, 10(1), 36.

They are not very current papers, but they are useful and from great researchers.

Best regards