I have tried a few buffer to desorb creatinine. but couldn't get good result.
I would suggest to use organic solvent such as toluene, dimethylbenzen
sonication(ultrasonic bath), may be boiling of activated charcoal in organic solvent . The most conventional way of regeneration is the burning
What type of organic compound? This might help to identify an appropriate method.
Some compounds are very hard to desorb. For example, many phenolic compounds are painfully difficult.
If the cpd is stable to heat and you know of a suitable solvent it would normally be soluble in: then a Soxhlet extraction could work.
Take a look at https://en.wikipedia.org/wiki/Soxhlet_extractor
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