I'm not sure if I understood your question, but in order to run an industrial process efficiently, one must start with the first, most important step: creating a mathematical model that captures both the transient and steady-state characteristics of the system. The model should explicitly indicate any inputs that cause a disturbance as well as the system's inputs and outputs. Then, based on the system's open-loop performance, you can select a suitable control strategy from the wide range of alternatives described in the literature.