Hi,
I am setting up an esterification reaction using EDC/DMAP for R-OH and R'-COOH conjugation in water. However, one of my reactants R' also has an amine (-NH2) group. I am curious as to how the reaction would proceed with EDC and DMAP? And the conjugation would be between R-OH and R'-COOH, and not between R'-COOH and R'-NH2.
Thanks in advance,
Aazam