How to prepare FESEM samples for nanostructured lipid carriers?

01 January 1970 1 6K Report

I have prepared 3 Nanostructured lipid carrier formulation with size range froom 90-160nm.What is the best way to prepare FESEM samples for good surface imaging?

Arijit Ghosh

You may refer to the following articles:

http://www.fischione.com/uploads/Files/JA002.pdf

http://www.sciencedirect.com/science/article/pii/S0927776515000971

http://www.sciencedirect.com/science/article/pii/S2213343716300549

Badges
Science topic

More Parikshit Banerjee's questions See All

If a journal doesn't provide doi after acceptance of the manuscript, is it authentic?

It is related to submission of the manuscript in a Journal and the process of its online availability.

18 February 2021 9,269 5 View

How can AI be used for enabling Design for Sustainability?

Design for Sustainability (DfS) is a wicked and complex problem. It needs the designer to combine specialized knowledge from several disciplines with systemic thinking. The designer also needs to...

05 February 2021 2,998 9 View

Des anybody have a straight forward protocol for invasion assay using colon cancer stem cells? Is there necessary to dilute the Matrigel?

I am working on colon cancer stem cells to see the impact of combinational therapy.

23 December 2020 9,830 3 View

Is there any software (windows) or spreadsheet except MELTS to understand fractional crystallization behaviour of volcanic rocks (i.e. basalts)?

I have bulk rock major and trace elements data available to me.

17 November 2020 3,531 3 View

Have anyone used galaxy server ?

I have 4 fastq files. From some earlier post I tried to analysethrough Galaxy sever. I used "fastp", "clip adapter" and also "trimomatic" separately three different times to trim adapter. As I...

05 November 2020 1,589 1 View

How to scale an image whose scaling details are unknown?

I want to know how to add scale bar to a histopathological image using ImageJ whose image scale was not recorded at the time of taking the image.I got to know from the technicians that 1micron is...

03 November 2020 10,009 3 View

How to do scoring for fat droplets in Histopathological sections?

I want to do scoring for macrovesicles and microvesiclular fat diposits in Histopathological Liver sections. Can anyone suggest me a software and discuss a suitable protocol to achieve this. I...

18 October 2020 9,727 2 View

Significant value post Bonferroni correction?

Hi I did Friedman's RM ANOVA and found data is significant.Then Wilcoxon posthoc analysis is showing significant differences, p=0.001.But Bonferroni adjusted significance is bringing p value to...

07 October 2020 1,262 3 View

How to remove background and gridlines of graph in R?

I am trying to remove the background & gridlines from my Violin plot drawn by R. Please let me know the script/method. Also please let me know method to move the axis title n graph title in R....

07 October 2020 391 4 View

How to underatand whether to consider Linear, Quadratic or Cubic regression equation?

Hi I want to understand the relationship between two variables using correlation and regression. I performed Normality test and my data is parametric.After doing scatter plot analysis I observed...

29 September 2020 9,533 10 View

flexibility of polymers chain

effect of double bond on the flexibility of polymers

07 April 2021 0 0 View

Formulation of polymer color flakes

I am writing to request some information for making polymer color flakes. I would appreciate the help.

17 March 2021 0 0 View

Does any one know how i can prepare liver tissue with transmission electron microscope with good fixation?

i have problem in preparation of liver tissue with bad cell organelles and how i can adjust osmolarity

03 March 2021 8,890 1 View

What is the production process of CaFe ferroalloys?

I looking for ferro calcium production process

03 March 2021 1,755 4 View

I need to image mesoporous silica nanoparticles that are in ~100 nm size and do high resolution TEM to look at mesopores. what grids should I use?

Need to image mesoporous silica nanoparticles using the TEM. Also, need high resolution TEM images to see the mesoporous structure. Kindly suggest what kind of grids to use. Thanks, Shatadru

02 March 2021 1,787 2 View

Is there any test to determine the cardiovascular risk of patients with obesity? from the perspective of obesity?

We found tests to determine cardiovascular risk taking into account lipid profile, blood pressure, age, history of diabetes, other laboratories. But when weight is involved, there is a paradox. I...

02 March 2021 6,036 1 View

12% ledeburitic cold work tool steel, etched for revealing retained austenite, any help for clarifying?

Hello everyone. Given microstructure image belongs to a 12% ledeburitic cold work tool steel (annealed and tempered). The sample was etched with picral (100 mL ethanol and 4 g picric acid). I...

02 March 2021 4,119 3 View

Is There Any Feasible Method To Test Fluorescent Compounds Other Than Fluorescence Spectrometers ??

Is There Any Feasible Method To Test The Efficiency Of Fluorescent Compounds Other Than UV Spectrometers ? Suggestions Would Be Appreciated !

02 March 2021 5,785 3 View

Shall I skip the measurement model in SmartPLS?

Hello everyone, I had run a mediation model in SmartPLS using questionnaires that were already validated among my statistical population. A professor who edited my paper -though she is not...

01 March 2021 3,052 3 View

How Can I bring as much common elements in steel as possible to calculate stable phase(s) in OpenCalphad?

As I was tweaking step-by-step OpenCalphad6 Macros step1.ocm involving phase and thermal property calculation of a High-speed steel, I could not incorporate more than 6 elements in the steel...

01 March 2021 8,840 1 View