Hello everybody,

I was wondering about how to assess (changes in) selectivity in a given dataset. Let's say we have a distribution of different values (e.g. responses to some stimuli.). Only some of these values are high. Some thoughts were that I could look at the variability (e.g. standard deviation), which would give me some information, or at the proportion of values >X (i.e. number of values >Y / total number).

But there is a potential problem: Let's assume now the values are reduced overall. This would immediately also change the two measures. However, it could well be that most values are reduced, while a few remain the same or are even increased. In other words, selectivity increases (e.g. higher responses to a few stimuli, but for the rest going down). Anyone an idea on how to best measure such (changes in) selectivity beyond standard devivations or proportions (given that they are also changed by an overall reduction)?

Thanks, Stefan

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