Hello Dr Sharma, I used a program called meta which was dos based for a PB of a diagnostic dataset, It is a long time ago, I cannot use the program now as computer died that could run dos based programs. I can send you some files though, but it is not really of much help as I would not recommend that program given there are much more current ones. I recall some authors I looked up at the time, Prof. Glasziou, Prof. Irwig both had published manuscripts on PB. I can find these references for you if required. Thanks Debbie