how to isolate/ separate 1-(3-hydroxy-4-nitrophenyl)propan-1-one, from 1-(5-hydroxy-2-nitrophenyl)propan-1-one ?
while on nitration of (3-hydroxyphenyl)propan-1-one obtaining two products those are 1-(3-hydroxy-4-nitrophenyl)propan-1-one,1-(5-hydroxy-2-nitrophenyl)propan-1-one among this required product is 1-(5-hydroxy-2-nitrophenyl)propan-1-one. how to separate / isolate 1-(5-hydroxy-2-nitrophenyl)propan-1-one from other.
how to decrease / control formation of other product i.e [(3-hydroxyphenyl)propan-1-one] in the reaction. is their any condition / additive to control the (3-hydroxyphenyl)propan-1-one formation..?
reaction scheme attached below.
thanks.