Hi,

I am looking for suggestion for measuring NCV in mice. Recently, we purchased NCV measurement device, AD Instruments, Australia. We tried to optimize the protocol in mice from various literature search. We could get the sharp curve ( Action Potential) upon stimulation of sciatic nerve. However, we were unable to find the difference in latency between proximal and distal site of sciatic nerve (both values coming same) and ultimately unable to calculate the nerve conduction velocity.

Is there any way to overcome this latency problem?

Thank you in advance