How to determine more than two unknown parameters (bo, b1, b2) of a multiple regression.

Given than

Y= b0+ (b1 x1)+ (b2 x2)

If given that all values of Y and values of X1 & x2.

How to calculate b0 (intercept) and b1, b2.

as well as regression coefficient value (Rsquare)?

Kindly suggest Any statistical software (excel, matlab, SPSS) step wise solution.

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