I have an ICP-MS measuring metals in drinking water. Dissolved Ca precipitates on the cones and causes a decrease in instrument response quickly over time. For example, only 10 samples of high-Ca water will cause a 15% decrease in instrument response. I can follow the decrease in response by running check standards every 10 samples. Is there a way to re-calibrate the slope (or 'reslope') every 10 samples by re-measuring only one standard solution, instead of re-calibrating (10 cal standards) every 10 samples? Or is there another way to correct for drift?

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