An important transmissible parameter identified is the reproduction number (R), which is defined as the average number of secondary cases generated per typical infectious case. By knowing daily new cases, how can i estimate R0 and serial interval? I used edgeR package and the example I used worked. However, when I tried my own data. I got stuck when specify the mean and SD of serial interval. I used the published values in this article (mean=3.96, SD=0.21). I got the R0 to be equal to zero?!
Article Serial Interval of COVID-19 among Publicly Reported Confirmed Cases
Thank you