Combined therapy is effective, however, clients newly diagnosed with TB and HIV co-infection may not tolerate both drugs well. Start anti TB before ART initiation.
Combination of TB and HIV therapy is effective. But anti-TB must be started between 2 and 4 weeks earlier to reduce the risk of Immune Reconstitution Inflammatory Syndrome (IRIS). This should also be improved by pre-treatment counseling of the infected and affected (relatives and caregivers).
Combined therepay for TB/HIV co-infection is effective, for a newly diagnosed HIV with TB, needs to start ant TB for the first 2 weeks, while assessing, IRIS, then we introduce ART based regimen, however remember to effect of rifampicin to DTG, we need to double the dose of DTG, as far as TLD based regimen is concerned, as this medication lowers the level of rifampisin, therefore, be cautius while administer TB drugs with the ART, know the issue of drug-drug interaction, thank you