Most of the literature says mediterranean Diet Reduces the Adverse Effect of the TCF7L2- rs7903146 Polymorphism on Cardiovascular Risk Factors , Stroke Incidence , obesity and Diabetes.
On the other hand Thrifty Gene Hypothesis via 65 Loci Associated with Susceptibility to Type 2 Diabetes are the common hypothesis.
Some dietary supplements and medicinal plants shows their active actions on fat reduction and STZ induced rat for diabetes control.
TCF7L2 gene expresed in pancreas tissues of Type 2 diabetic rats where the rats are STZ induced. We have found number of scientific literature on medicinal plant extract showes their actions against STZ induced rats.
If some medicinal plant oriented Diet have their own activities on STZ induced diabetic rat and STZ has effect on TCF7L2 gene expression then the plant may active on TCF7L2 gene expression.
Need proper guideline for this theme.
Thanks in advance.
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