In cellular physiology modelling, esp. excitable cells, nernst potential can be taken as constant. That depends the ions' concentration does not change fast. So I am curious how fast can [Na+]i, [K+]i, [Ca2+]i change in live cell?
Albertino Bigiani
One factor affecting the rate of concentration change is the cell size: which cell type are you referring to?
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Xin-Yu Wang
Thanks Bigiani! Currently my concern is phagocyte. Is it non-excitable cell? What I want to know is which type of cell can give the quickest change and how quick? At least as far as you know.
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Albertino Bigiani
Have a look at this paper on the rates of diffusional exchange between patch pipette and small cells. Maybe you'll find the answer you're looking for. Good luck!
Albertino
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