The angle of repose of the powders would be significant, if you intend to consider the V-shaped tumble blender ─ which is a typical dry powder mixer often selected for manufacturing scale application.
Let the 'V' angle be of α degrees; in principle, one should ensure α < 180º - 2·θ, where θ stands for the higher angle of repose of the powders to be mixed. With 75º ≤ α ≤ 90º ─ to follow the question enunciate ─ we may expect to mix with acceptable efficiently powders of poor flowability, with 45º < θ < 52º, and also those of better flowability (θ ≤ 45º); but the blender can be expected to be less efficient with powders of very poor flowability. The powder capacity for efficient mixing with this type of blender can be expected to be maximized for a 'V' right angle, comparing with a lower angle (α < 90º). Therefore, we may keep the right angle for powders of good or fair flowability (θ ≤ 45º).
With angles higher than 90º there is little powder movement. With angles lower than 90º there is no transfer of powder from one side of the V to the other.
About predicting a suitable rotating speed for a V-shaped tumble blender please check my answer given elsehwere at this forum: https://www.researchgate.net/post/How_do_I_test_the_performances_of_a_self_developed_table_top_V-blender_machine