How do I get the primary structure of a new peptide assessed for conformity (with 2 to 7 amino acids)?

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Hey dear researchers, please how can I to solve this problem in CMG GEM?

I am working on an unconventional reservoir simulation coupled with geomechanics, but I faced this problem for a couple weeks already. I need help to solve this problem,...

13 February 2022 8,577 0 View

Convert Tdms file into CSV with python for spectral data analysis?

Dear all, I am trying to figure out how to convert TDMS files (channels properties) created with National Instruments LabVIEW into CSV using python. I am looking for a solution that would let me...

09 February 2021 3,469 3 View

The best way to study molecular population genetics of reef-building corals (mtDNA? microsatelite? others?)?

I am an "ignorant" of molecular approaches to study population connectivity or population genetics at the molecular level and wondering what would be the best approach to do so for coral species....

11 December 2019 6,519 3 View

Is it possible to make HPLC standard curve with 10mg standard?

Dear colleagues, Currently ,I am making some new molecules by enzymatic catalysis, due to the fact that I do not have standards for these new molecules, I decide to make indirect quantification...

26 September 2018 6,693 17 View

How does asbestos react in benthic or pelagic environments?

Is there any scientific investigation done on the effects of asbestos (Amiante in French) related pollution in the aquatic/marine environment?

26 February 2014 2,296 8 View

Do the goals of agricultural research in sub-Saharan Africa meet the needs of growers?

In many countries weed control, soil fertility and the lack of effective water management (both drought and flooding) are the most important impediments to farming. Unfortunately, relatively very...

13 December 2012 155 2 View

How do I conformally do PR spin coating on trench structure?

I did PR spin coating on trench structure. I used AZ P4620 PR and the thickness or PR is around 11um. The substrate is Si. And my trench structure depth is 141um(negative way). Even though I...

08 August 2024 2,298 0 View

How to increase simulation box size?

We intend to study the interaction between peptides and polymer (like PP, PE and PS) through MD simulations using Martini force fields ( Martini 2 for PP and Martini 3 for PE, PS). We have...

08 August 2024 4,842 0 View

Separation of organic acids-HPLC?

Hello What should be done to separate and identify organic acids in HPC when their RetTime is the same?Like oxalic acid with Propanoic Acid.or acids that have a very close RetTime.

07 August 2024 8,782 3 View

Unusual intensity drop in some sections of chromatograms in DDA?

Hi, we have measured tryptic peptides using both DDA and DIA method on QExactive. In DDA replicates i saw unusual intensity drops occurring at the same sections of chromatograms in DDA replicates...

07 August 2024 3,218 4 View

Research Methodology - Impact of Corporate Reputation on Stakeholders Behaviors?

Please can anyone support with the survey questions based on RQ measures and propose how to do it in FMCG industry and include as well the role of brand equity Thanks

06 August 2024 949 0 View

Anyone having idea about VN primer for miRNA primer design ?

How to design VN primer to attach with universal reverse primer

05 August 2024 2,116 3 View

Determining the worth of a point improvement in Hamilton Depression Scale?

Dear readers, Thanks for your attention. I am wondering about the health economic problem of quantifying the value of interventions which a) prevent, b) improve symptom profile and c) ultimately...

05 August 2024 3,246 1 View

How to analyze multiple phosphorilation sites?

Hello, I am currently analyzing some phosphoproteomics data, but I have peptides with multiple phosphorylation sites or phosphorylations together with carbamidomethylation or oxidation. How can I...

04 August 2024 8,432 3 View

Should I remove an item from a scale to raise Cronbach's alpha and McDonald's omega or is it better to leave it if they are both over .7 already?

Hello! I have this scale which had 10 items initially. I had to remove items 8 and 10 because they correlated negatively with the scale, and then I removed item 9 because Cronbach's alpha and...

01 August 2024 4,606 7 View

Recovery rate after peptide desalting using Sep-pack C18 1 cc Vac Cartridge?

Recently I'm trying to use Sep-pack C18 1 cc Vac Cartridge (Waters: SKU: WAT054955) to desalt digested peptides. However, the recovery rate is usually 40-60%. What is the normal recovery rate?

31 July 2024 6,544 11 View