Every journal has a different spectrum of readers with varying fields of interests.
Independent of the journal, a good question and a stunning way to give a surprising answer may refresh reviewers as well as readers. If you read several journal articles and you feel stimulated: then this is your journal. Find out where you belong to. Size and quality of your data may be differently seen by others though.
Submit after thoroughly studying the authorship comments. If your submission is accordingly, reviewers are able to give helpful critique. Take comments as opportunity to improve your manuscript.
You may find good articles in Pubmed (PMC) with keywords "publishing medical journal", but the best is an experienced scientific author whom you trust and who trusts you. He may guide you this long and arduous way.
hello an interesting question to answer. in my opinion i feel that you have decide what type of data you have and what level you have done the research. Then you decide the journals by reading the instructions and latest articles in that journal. if you are doing this much homework;definitely it is going to help. But, if you are blindly sending the article then it comes back most of the times.
As my experiences most of the times only small corrections that too in the references we have to do. And i will discuss one of my experience that i am basically Physiologist but did a study on depression of postgraduate students and sent the article to one of the psychiatry journal pubmed indexed. The article was rejected saying that i have to do on different scales not the one which i have used.