You are an expert, the only way to use genes in a safe and ethical way is to count on the opinion of patients. Informed consent and non-malfeasance dictate what to do in the case to which you refer. But I am sure that this is something that you know much better than I do.
My warmest greetings and I wish you many more successes in your rich professional activity.
Any intervention that causes changes in the basic mechanisms of mankind lives, and potentially impacts on future generations, is a topic that concerns us all, not just professionals.
So, I believe that's the intent of the question.
In my opinion this is not a question for insiders only.
We need to open a debate, at various levels, involving several figures who can interact in the context of complexity.