How to highlight novelty in your research paper?

I have come up with a method and had written a paper on it. Paper got rejected by a journal stating that there is no theoretical novelty. I am kind of confused on why the novelty that I am able to...

28 February 2021 2,393 8 View

I have genotype gvcf of 30GB , which is causing an issue in analysis. I was wondering if there is a way to get around the size issue ?

I have a genotype gvcf of significant size, which is causing an issue in analysis. I was wondering if there is a way to get around the size issue and run the genotype gvcf in R or do I need to...

09 February 2021 4,178 4 View

How do I analyse a Photoluminescence Spectrum ?

I have a few questions related to PL (images attached for same material by 2 methods), It would be great to get some help. 1. What is the physical meaning of highly intense PL? Does this mean...

02 February 2021 1,791 3 View

How to choose the electrolyte for (electrochemical impedance spectroscopy) EIS ?

Hi, I am working on a multi cationic material that has Li in it. I wish to measure the conductivity of my sample. We have a 3 electrode system with Ag/AgCl as a ref, platinum, and glassy carbon...

29 January 2021 405 2 View

Rhodanese enzyme assay using salt potassium ferricyanide?

I wanted to perform rhodanese enzyme assay using salt potassium ferricyanide (K3Fe(CN)6). The assay is based on the products formed in the reaction but I can't get the reaction i.e what product...

26 January 2021 8,044 4 View

How stiffness matrix modification after hinge formation is done for pushover analysis?

Can anyone please explain this? How do I account for plastic hinges in my model and how do I modify the stiffness after plastic hinge is formed? Need a small example. Thank You

15 November 2020 1,967 3 View

How to analyze nominal/ordinal data in cases where you are testing multiple drugs/ infection against common risk factors?

chi-square or Fisher exact test I have a statistical question about chi-square and/or Fisher exact test. I have a cohort data studying the cause of infection in BRD with variables such as age,...

28 October 2020 2,589 1 View

What vehicle to be used for the drug loaded nano chitosan-pectin nanoencapsulated powder?

I want to know about vehicle or solution that I can use for the dosing of drug loaded nanochitosan-pectin nanoencapsulated powder?

25 October 2020 3,890 3 View

How to get rid of a constant peak at fix RT every time in HPLC ?

I am running catecholamine standards in HPLC using UV/FLD detector. I am getting a constant peak at fix RT (retention time @ 3.5 min, image enclosed) every time, even if I run another standard or...

29 September 2020 847 7 View

How to use 5 by 5 or 7 by 7 kernel size for a deep learning network with 3 by 3 kernels?

I am using a U-Net architecture with Xception net as encoder . The visual area of the segmentation mask is very small and after training, it is giving a lot of false positives. I am thinking of...

20 September 2020 1,968 2 View

Is it possible to set a breakpoint at a specific DYNAMIC instruction using the GNU Debugger (GDB)?

Using GDB, it is straightforward to debug and monitor a target program by setting a break-point at a specific instruction, since the instruction addresses are known. However, we have two...

24 February 2021 1,598 2 View

How to reduce static electricity of powder after lyophilization?

I am working on synthesizing and then purifying peptides using the SPPS system. After purification of the peptide, the peptide powder is obtained using a freeze dryer. When measuring the powder,...

22 February 2021 10,099 5 View

Buillding 3D Model Fussion Protein with Modeller?

Hello May i ask you about using Modeller for making 3D model fussion protein. I want to build a fusion/chimera protein structure which is including 2 different protein and then evaluate quality...

09 February 2021 9,369 2 View

How to obtain the plot of frequency shift w.r.t. pressure in a micro resonator (cc beam) based MEMS pressure sensor in COMSOL?

I need to know how to plot the impact of pressure (0 - 100 kPa) (which is applied on the back side of diaphragm) on the frequency shift caused in the cc beam supported on the diaphragm with...

01 February 2021 5,805 17 View

Can we incorporate unnatural amino acids into protein using software for graphical image purpose?

I am looking to incorporate a unnatural amino acids which is not available in the swisssidechain database into a protein crystal structure of pdb? I am using chimera 1.14 vis. tool?

26 January 2021 4,064 3 View

Can't generate a mash for topology in ANSYS. how to do it?

Created model of steel caisson in space claim. Used a static structure for topology. But there's an error "one or more surfaces cannot be mashed with acceptable quality", " One or more entities...

25 January 2021 893 1 View

What are some properties of a proton in a static B-field?

I have some basic questions about the behavior of a charged particle in a static B-field. 1. Without a B-field, the particle has spin, with random orientation and spin frequency. a) What...

24 January 2021 1,389 3 View

Abaqus CAE: Steps and applying loads using amplitude (static general) - why it doesn't work as expected?

24 January 2021 2,146 2 View

Best tool to build missing residues, minimize and validate a ligand model?

I am working on a ligand that is co-crystalized to parotein, but the ligand is missing some residues that makes it appear as if it was separated into two ligands! what I need is to connect them...

23 January 2021 3,975 7 View

How to view the electrostatic potential value of a Gaussian09W result?

Hi all I am able to view the electrostatic potential surface using Gaussview to see the calculating result from Gaussian09W of a small molecule. However, the strength is represented by color. I am...

19 January 2021 5,448 3 View