OAS-POSS-NH2 (OAS) can be obtained in a two steps.
Fist: hydrolytic condensation using commercially available (3-aminopropyl)triethoxysilane (APTES) and appropriate amount (relative to APTES) of hydrochloric HCl (3.6 eq), trifluoromethanesulfonic CF3SO3H (1.5 eq), or trifluoroacetic CF3COOH (1.5 eq).
Second: neutralization earlier obtained salt by Amberlite resin (base form).
It is worth noting here, that the synthesis of OAS and its derivatives forces strictly anhydrous conditions. Otherwise, in such a condition the formation of open cage-like. for more details see (paper with experimental):
https://www.researchgate.net/publication/265096300_High-Yield_Synthesis_of_Amido-Functionalized_Polyoctahedral_Oligomeric_Silsesquioxanes_by_Using_Acyl_Chlorides
If you would like obtain T10 POSS-NH2 see:
https://www.researchgate.net/publication/281346929_Novel_organic-inorganic_hybrids_based_on_T8_and_T10_silsesquioxanes_synthesis_cage-rearrangement_and_properties
PS. Synthesis is very easy. If you have more question, just ask.
Article High-Yield Synthesis of Amido-Functionalized Polyoctahedral ...
Article Novel organic-inorganic hybrids based on T8 and T10 silsesqu...
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