How can i measure kinetic stability of my protein during a single mutation by MD simulation or other computational/ online ways?

Hossein Mohammadian @Hossein-Mohammadian

12 October 2016 1 8K Report

hi every one

i introduce some single mutation on my protein in silico to investigate stability of them without any deficiency on its activity

how can i measure kinetic stability of my protein during a single mutation by MD simulation or other computational/ online ways?

Karim Mahfouz

hi hossein

by enhancing the rigidity of the flexible segment within the active site it provides an efficient method for improving enzyme kinetic stability.

then use program below to measure kinetic stability

https://bioinformatics.ca/links_directory/tool/13189/popmusic

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