If you can use Rate based Modeling then you may be able to approximate column size. If you go for Equillirium method (e.g. Murphy efficiency) then you can approximate the number of trays. However to ensure columns hydrodynamic integrity you may use Column Hydraulics Calculations software such as KG Tower SulCol etc.
I mean to say you have to use multiple tool to size the column if you model cilumn by Equillirium method.