Recently I am involved in the modification of cyclodextrins. How best to remove modifying particles from the interior of cyclodextrin. These compounds are soluble in water, methanol and ethanol. Thanks in advance for your help
Add an inorganic solvent that displaces the particles. Many CD's will loose their guests with strong organic solvents such as acetonitrile. You will likely need to find something that the guest is soluble in.