Manipulation is kind of vague information.But if u mean HVLT techniques without corrective exercises it has been futile at quite a number of times.

I agree the given information need to be more detail

Dear colleagues,                                                                                                                 The discussion about side effects and serious complications from manual therapy has long been held (over 50 years). It is very important to reduce the incidence of side effects and complications after spinal manipulation (not exactly known; estimation between one dissection of the vertebral artery in 5,000,000 therapy sessions, to one cerebrovascular accident in 4000.000 cervical manipulation and one cerebrovascular accident in 100,000 Patients aged

Dear all

sorry for uncleanness 

I do mean the  HVLT techniques for spine in percolate. because, I have been practicing it for the last 12 years or more but I do not get any negative feedback though I did not follow my patients too.