I have just been through the process of adding diphtheria toxin to our animal use protocol. As per guidance of the environmental health and safety committee they do not require biosafety housing. E.g. the mice are injected in biosafety hood and returned to regular housing with a note on the cage that they received the toxin. In case of leakage from the injection site or if necropsy is performed within 1 month after injection the mouse/carcass needs to be under biosafety conditions.

I have the exact same question.

Did you find any information about the excretion of DT in mice?

Thanks

I have the same question, does anyone have a reference for the excretion of DT from mice.