Turmeric is a golden spice famous for its culinary use in Asian cuisine. Its use has not been limited to lucrative food preparation since antiquity. Curcumin, one of the highly valued natural compounds, underlies the use of turmeric-based formula in traditional medicine. Can we find any systemic area which lacks curcumin-directed traditional knowledge or scientific evidence of curcumin-based research? So, why this nature's gift still could not find its way to conventional medicine?