We are finding that family conflict and closeness seem to be more related to girls' substance use (alcohol in particular) than boys. Interested in international research on adolescent gender and factors predicting substance use.
we did a cross sectional study that may partially inform your question. see
Wood, A.P., Dawe, S., & Gullo, M. (2013). The role of personality, family influences, and prosocial risk-taking behavior on substance use in early adolescence. Journal of Adolescence, 35, 871-881http://dx.doi.org/10.1016/j.adolescence.2013.07.003
let me know if you need a full text sent to you. sharon