I don't have a microplate reader in my lab now and using a cuvette-type UV-Vis spectro is kinda "wasteful" in terms of how much of the treatment solutions I'll be using. So I thought of using a nanodrop for biofilm quantification.

Of course I'll be looking at the differences in terms of absorbance readings of Crystal Violet-stained biofilms using nanodrop and cuvette-type UV-Vis spectro firsthand. But I'd like to know if anybody has tried it before? How was your results? Are there any significant differences?

Thank you!