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22 February 2021 9,932 11 View

G-mmpbsa- file error during one step calculation?

Hello, I am using the one-step approach from https://rashmikumari.github.io/g_mmpbsa/single_protein_ligand_binding_energy.html to calculate binding energy between protein and ligand. However, I...

09 December 2020 7,302 1 View

In colorimetric analysis, can we compare absorbance measurement from spectrometer and optical density measurements from image analysis using scanner?

There are two most popular methods for colorimetric analysis i.e. spectrometer data and image analysis using a scanner. For example, in order to study the color intensity of films, I have measured...

01 June 2020 4,911 1 View

Can we expect a reduction in the population of particles in SEM images in the form of particles and after making their films?

I took scanning electron microscope images of my samples in powder form and after coating their films. In powder form, a large number of particles can be seen however, in the films only a few...

21 July 2019 8,454 3 View

Is it possible that conscientiousness and openness to experience correlate with each other?

Is it possible that a person is both highly conscientious and highly open also? I conducted factor analysis on responses of personality traits namely conscientiousness and openness to experience...

17 June 2019 7,297 8 View

Wireless Personal Communication journal? Standard first round review time and Decision process?

Dear Friends I hope you also have submitted the paper in the Springer's Famous Journal for Wireless Personal Communication. I have submitted in December 2017 and still the Journal have not found...

25 February 2019 2,746 4 View

DNA isolation from mouse lungs?

Dear all, I want to isolate DNA from mouse lungs to check for gene deletion (The Cre is expressed specifically in Type II alveolar cells). I tried to isolate the DNA using the method discussed...

12 February 2019 5,159 5 View

What can be the ideal rheological characteristics of a polymeric solution used for oral drug delivery?

Hello Everyone, I have made the polymeric solution of two different polymers. My aim involves preparation of beads from this polymeric solution and encapsulation of my drug to these beads that I...

26 August 2018 6,958 11 View

Which solvent is suitable for analysing the UV Vis spectra of a polydiacetylene compound?

I want to study UV Vis spectra of a polydiacetylene based compound. It is a polymer and is not soluble in most of the solvents. i tried dissolving it in ethanol, butanol, chloroform, DCM, THF, DMS...

25 October 2017 6,598 3 View

What makes some of the diacetylene compounds highly UV sensitive?

16 June 2017 9,731 3 View

How to analyze a particular region of my simulation box in GROMACS?

Hi, I am using GROMACS 5.1.4 to simulate water in contact with a surface. I am only interested to calculate some properties of water near the surface. Let's say at a distance of x nm from the...

03 March 2021 9,989 2 View

Does anyone know HRM channel in a 2 plex QIAGEN Rotor- Gene Q qPCR can be used as a separate channel?

I am going to have 3 different probes in my qPCR work that I am going to do. But I realized that the machine we have in the lab is a Rotor-Gene Q 2plex HRM Platform, saying it has green, yellow,...

01 March 2021 8,544 1 View

Is there a deep reason for using the squared modulus of the wave function as the probability density of the existence of the particle?

I think we were all surprised at the first time we got to know quantum mechanics that the squared modulus of the wave function is the probability density of the existence of the particle? The role...

28 February 2021 6,282 9 View

How can I calculate the rdf of water molecules around 'Na' ions that are closest(adsorbed) to the nanoparticle(solute)?

Hi, I want to calculate the radial distribution function for water molecules around the Na+ ions adsorbed on the surface of a spherical nanoparticle using the gromacs trajectory dynamically? For...

28 February 2021 5,650 1 View

How can I assign a velocity along one direction to CO2 molecules in a molecular dynamics simulation using GROMACS?

Dear all, I am trying to perform a MD simulation about the interaction between CO2 and a polymer. I create my model, solvate it and perform the NVT and NPT equilibration. Now I am not able to...

26 February 2021 10,014 3 View

What could be reason for getting such type of graph for complex impedance in case of polymer blend films?

Its effect appears in real part of ac conductivity also. Can anyone suggest any reason behind it?

26 February 2021 3,487 3 View

How does GROMACS calculate the average structure of proteins?

I want to get a average structure from a pdb file containing multiple models. I used the command below: gmx cluster -f input.pdb -s topol.tpr -cutoff 20 -method gromos -av GROMACS...

25 February 2021 6,314 1 View

How to measure angle between laser travel path and machine axis in Laser Measurement system?

25 February 2021 1,987 3 View

IF troubleshooting: looking at an intracellular protein that localizes to the cell's and how to reduce increase in signal due to cell ruffles?

I am currently trying to stain for PI3KBeta in MDA-MB-231 cells. My current issue is that 1) beta stains all over the cell and 2) there is an increase in signal at the edge of the cell and this...

24 February 2021 8,582 1 View

How the Ground Plane implantation is performed without damaging (and w/o varying the undoped nature) the top Si (8-10 nm) in FDSOI technology ?

It is a general practice to introduce Ground Plane in FDSOI devices under the BoX. The Ground Planes are introduced by Ion Implantation through Top Si layer and Buried Oxide. I wanted to know that...

24 February 2021 5,974 4 View