Non adherence to take medications as prescribed contributes to the indirect costs of non communicable diseases worldwide, and impact patient's safety too. Non adherence is not amenable to be assessed as a single variable measurement as it is a process made of multiple dimensions.

I built an E-tool around the idea that sedentary behaviour impacts the patients' adherence to take medications as prescribed as a consequence of a causal pathway where the relationship of disease upon personal wellbeing is mediated/moderated by more severe local and systemic inflammation in sedentary subjects. In addition, the association between sedentary behaviour and poor adherence might mediate the burden of infections-driven exacerbations across the more vulnerable layers of city dwellers.

A pilot study is now needed to validate the e-tool, which has the potential of new capacity building in terms of improving patients safety, and to be deliverable to health care facilities at international level.

The developmental objectives foreseeable for the E-tool implementation are to contribute to:

i) protect vulnerable subjects against the risk of non adherence; ii) improve the effectiveness of patient-professional communication to optimise the adherence, as well as the readiness of public health facilities to meet the needs of their citizens, above all the more vulnerable layers of the population; iii) collect population indicators to get better understanding of interaction between infection, immunity and inflammation across different climates, races and nutritional habits, to then identify optimal public health interventions and cost effective treatments.

I asking for demonstration of interest in my project.