Many nutritionists are not sure about the efficacy of them due to: (i) their lack of knowledge on active compounds and their dose; (ii) technical data sheets and labels do not provide with data about the plants/compounds contained nor their proportion/quantity.
Moreover, extraction and homogenization has been always a problem for manufacturers.
Finally, regulation is changing, limiting the number of allowed active compounds and their regulatory category/function: flavours vs growth promoters vs health promoters. Also, regulations will possibly force to declare all the compounds and their quantity.
All in all: how do you think this topic will evolve?