How to calculate the fraction metabolized of a drug by an enzyme using clearance(ml/min) values of the metabolite formed?

I am trying to find the fraction metabolized of a drug by CYP and UGT enzymes. I am unable to get the values of fraction metabolized (Fm) directly from the literature. Can we calculate the Fm of a...

21 February 2021 5,379 2 View

How to compile UDF for parallel processing ?

I am trying to use a UDF for velocity input in the room from a fan. I have created a UDF but when I am trying to load the UDF it shows an error stating that it is not compiled for parallel...

03 February 2021 2,187 3 View

What will be the life of siRNA (liquid form) at -20 degree, if kept unopened?

Hi all, I just want to know that, if we keep the siRNA in a -20 degree freezer (as mentioned in the product detail), what will be the average life of the siRNA? Can we store for more than one...

10 January 2021 6,346 6 View

Is there any method to convert color on nitrocellulose into digits (numbers)?

This is to design a protocol in which color obtained on nitrocellulose membrane can be converted or processed through any method to digits (numbers) to compare with different state of particular...

06 January 2021 9,309 1 View

Vertical distributions of SOC & N is found decreasing with increased value of bulk density, shown in literature, is it uniform for the forest soils?

Almost all the literature shows that the vertical distributions of soil organic carbon (SOC) & available nitrogen (N) is found decreasing with increased value of bulk density with respect to...

21 December 2020 670 10 View

Can difference-in-difference approach be used between two treatment groups?

I want to know if difference-in-difference approach can be used for two treatment groups. Can I use it it between them or should I first identify a control group and then compute the diff-in-diff...

20 December 2020 2,825 1 View

Is there any chemical environment or parameters to define or explain the sediment and soil profiles, are they separated by chemical parameters?

Sediment is relatively younger than the soil in the depositional environment as the sediments are consequence of the accretion of particles transported either by waters or by winds, whereas, soil...

12 December 2020 4,822 18 View

Bulk density obtained of the forest surface soils is 0.81 gm/cubic centimetres, is it normal?

Bulk density of a forest soil sample in a community forest created under social forestry scheme in the district of Nadia, West Bengal is obtained as 0.81 gm/ cubic centimetre, comparatively too...

30 November 2020 4,706 33 View

Is it possible to grow human breast cancer cell lines in immune competent mice?

Hello everyone, I am working in breast cancer and wanted to do in vivo studies in breast cancer mice models. Here we do not have the facility to maintain immune-deficient mice, and I have MCF-7,...

27 November 2020 1,638 3 View

What's the actual content of carbon in biomass, is there biomass carbon neutral or zero carbon?

The content of carbon in the biomass varies from 35% - 65% in one literature, in the another, it's 45-50%, though 50% is often taken as default value, and all they are surprisingly constant...

23 November 2020 1,736 7 View

Looking for Materials with high thermal expansion coefficient and high temperature resistance?

03 March 2021 8,272 1 View

Research on Supply Chain Management in Indian context?

Hi, I am planning to apply for the PhD degree in the Supply Chain Mgt. with specific area of "Cold Storage warehouses" during Pandemics and wars. Where lock downs and shut downs are frequent....

02 March 2021 285 2 View

Why do the air flow results vary totally when adding scalar in CFD ?

Dear All, We are using Autodesk cfd to calculate the air flow in a single sided naturally ventilated room, where air flow depends only on buoyancy due to temperature difference between inside and...

25 February 2021 9,602 4 View

What are the saturated salt solutions that can give specific relative humidity of 35%, 65% and 95% for conditioning wood specimens?

Due to the unavailability of climate rooms, I want to carry out an experiment that require the use of certain saturated salt solutions especially those that can condition the wood specimen to 35%,...

25 February 2021 8,139 1 View

What is the suitable range of Sulfur content and Viscosity of Heavy fluid Oil that used in Kiln?

What is the disadvantages of high sulfur content to the ceramic burning process? and what is the effect of outranged viscosity?

24 February 2021 8,219 2 View

EMSA troubleshooting. Protein-DNA complex not migrating, cold probe lane with multiple bands. Can anyone help?

I'm running an EMSA to show the DNA binding activity of recombinant proteins versus the Wild type. Previous assays run by my research group using a different test system show the protein-DNA...

24 February 2021 8,325 1 View

What would be the best method to study the seasonal variation in wetland vegetation?

I wanted to learn how the seasonal variation relate to climate change. The best samplimg methods are required. Therefore, any references or suggestions are welcome. Thank you

24 February 2021 8,589 3 View

Can anyone help or comment on solubilising chlorobutanol in aqueous injections in minimum time possible?

Please suggest solubilisation of chlorobutanol in injections. Tried pH and high temperature. But the issue is of assay drop. If anyone can suggest any solution. Its a commonly used excipient for...

21 February 2021 7,397 1 View

Is the box plot of climatic indices better illustrate from daily data or annual data?

Hello, I hope you have a good time. I work on a research project about temperature indices. Due to the high number of indices, I only work on tables and maps on an annual time scale. In other...

19 February 2021 9,742 2 View

Room Occupancy Calculation ?

15 February 2021 1,997 6 View