How can I exchange a hydroxyl for a sulfhydryl (thiol)? It can't be reactive to azides. I'm currently trying Newman-Kwart Rearrangement, so other methods would be good.
Dhanapal Ramu
Initially alcohol to convert O-mesyl followed by to make thio acetate using pottasium thio acetate,then the thioacetate hydrolysed by methanolic HCl.U will get thio as a product
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Dhanapal Ramu
Mitsnobu reaction with alcohol and thioacetic acid it will form thio acetate.After hydrolysis thiol will form and we can reduce two steps
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Shahid Mahmood
Alcohol and Lawesson, s reagent react with each other in the presence argon environment , and reflux in toluene 20 minute.
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