Engineering Blockchain Applications and AI-Blockchain Integration: Challenges, Solutions, and Future Directions

The convergence of Artificial Intelligence (AI) and Blockchain presents transformative opportunities across various domains, particularly in healthcare, cybersecurity, and IoT security. However, developing secure, ethical, and scalable AI-Blockchain applications requires addressing key challenges such as data privacy, transparency, explainability, and energy efficiency.

This discussion will explore:

  • Engineering Blockchain ApplicationsSecure software engineering approaches for blockchain applications. The role of blockchain in healthcare innovation with a focus on ethics and responsible AI adoption. Sustainable blockchain frameworks for healthcare and IoT security.
  • AI and Blockchain IntegrationAI-enhanced blockchain for automated decision-making and predictive analytics. Challenges in explainability and accountability in AI-driven blockchain applications. Privacy-preserving techniques for AI models utilizing blockchain technology.
  • Relevant Research Contributions

    For an in-depth exploration of these topics, the following papers provide key insights:

    • Ethics of Blockchain by Design: A responsible framework for healthcare blockchain applications. Blockchain in Healthcare Today (BHTY), 2025.
    • IoT Security Challenges in High-End Equipment Fault Diagnosis: A secure software engineering perspective. IEEE IoT Journal TechRxiv, 2024.
    • AI and Blockchain Framework for Healthcare Applications: A model integrating AI and blockchain for healthcare innovation. Facta Universitatis Journal, 2024, DOI: 10.2298/FUEE2401169R.
    • Secure and Sustainable Software Engineering Framework for Healthcare Blockchain Applications (S3EF-HBCAs): Addressing security and sustainability in blockchain-based healthcare systems. International Journal of Blockchain in Healthcare Today (BHTY), 2023, DOI: 10.30953/bhty.v6.286.

    We invite researchers and practitioners to engage in this discussion, sharing insights on best practices, innovative frameworks, and future research directions in AI and blockchain integration.

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