Does the NMDA receptor concentration in peripheric blood correlate to the concentration in central nervous system?

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Esat Adiguzel

NMDA receptors are in neuronal membrane, not free proteins in the peripheral blood. It is possible that to detect their metabolits (?) or antibodies against to NMDA receptors.

Murugesan Arumugam

I don't think so in density of the receptors. But there is a correlation of NMDA receptor subunits in human peripheral blood lymphocytes and opioid addiction (Eur J Pharmacol. 2010 Jul 25;638(1-3):29-32).

Camila Marcelino Loureiro

And about subunit GRIN1? Could I measure in peripheric blood?