15 December 2015 0 2K Report

Also, does it occur naturally in the human body just as L-tryptophan does? I am aware that there are tryptophanamide monomers in proteins and enzymes but if I am not mistaken, when these degrade they hydrolyze tryptophan, but not the amide. But i was wondering if the tryptophanamide on its own have any use by the human body or if it occurs naturally in our diet, or perhaps if it is a biological precursor in the body to the protein peptides.

And a last question--would supplementing isolated tryptophanamide orally act as a prodrug for tryptophan itself, or would it be the other way around? I ask because supplementing isolated tryptophan mostly gets decarboxylated into tryptamine right away, then indole 3-acetic acid, then indolol, which definitely doesn't lead towards an amide. However I heard some supplemented tryptophan will bind to enzymes and convert into tryptophanamide monomers.... is that true as well?

Thank you for reading and cheers

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