More recently, a partnership between cannabis research companies Pathway RX and Swysh Inc. and the University of Lethbridge in Alberta, Canada, found that certain Cannabis sativa extracts could be used in treatments to prevent infection with SARS-CoV-2, the virus that causes COVID-19.
Specifically, they found that the extracts have an effect on the expression of ACE2 and TMPRSS2, proteins in human cells that research has shown to be an entry point for the virus. However, their research has only just been submitted for publication and has not yet been peer reviewed.
Canabinoid is a constituent present in Cannabis plant. No doubt, Canabinoid has anti inflammatory effect. It has a potential use in even for HIV induced cytokine damage. Remember that Cannabis is a narcotic drug. Therefore, better to look for other plant based drugs which may have potential effect on cytokine storm in Covid 19 infection.
According to WikiPhyto Cannabis has some positive effect on the Broncho- dilatation and can be used to relieve the symptoms of asthma. So it is also conceivable to be of some help to relieve the symptoms of Covid-19 (breathing difficulty for example).
Cannabinoids such as cannabidiol (CBD) have a history of safe use and contain several properties which may be useful in treating certain medical symptoms: CBD has anti-inflammatory properties, can act as a vasorelaxant and has the ability to reduce pain and anxiety. In combination with other cannabinoids and terpenes, as well as necessary clinical intervention, CBD has much potential to treat the symptoms of a virus such as COVID-19. Whole plant cannabis extracts have also been shown to reduce blood coagulation in animal models; it is known that many of the negative systemic effects of COVID-19 appear to be related to altered coagulation, so it is possible that cannabis may be useful in managing these sequelae. arly findings in a study currently being conducted by terpene manufacturer Eybna and cannabis research and development firm CannaSoul Analytics, both from Israel, appear to indicate that the combination of terpenes and cannabinoids used is up to two times more effective than the corticosteroid dexamethasone, when used to reduce inflammation from COVID-19. The study has not yet been peer reviewed.
Cannabidiol(CDB) has anti-inflammatory effects. These effects suppress cytokines and de-crease chemokines, leading to suppression of effector T-cells, microglial cells, and overall host response to pathogens including viruses like SARS-CoV-2.
Article Cannabidiol as prophylaxis for SARS-CoV-2 and COVID-19? Unfo...
COVID-19 is a complex disease that may be considered to have phases. In certain phases anti-inflammatory agents may be beneficial and in others they may be harmful. For example steroids clearly benefit those with severe COVID-19 (i.e. if oxygen is required). However steroids may worsen outcomes in those who do not require oxygen.
Cannabis smoking can damage lungs and may increase the severity of COVID-19.
However, in select cases medical cannabis derivatives may be beneficial in the acute inflammatory phase of COVID-19.