What are the basic screening parameters for the chemical compounds to be an antiviral agent?
Is there any anti-retroviral chemical compound list available?
Dear Sayan,
The following links lead you to the requested list:
http://emedicine.medscape.com/article/1533218-overview
http://www.niaid.nih.gov/topics/HIVAIDS/Understanding/Treatment/pages/arvdrugclasses.aspx
Hoping this will be helpful,
Rafik
Dear Sayan Chakraborty
Pls. find the attached files, may help in your research, good luck
http://pubs.acs.org/doi/abs/10.1021/ci8004226
https://www.cdc.gov/mmwr/preview/mmwrhtml/rr5107a1.htm http://link.springer.com/article/10.2165/11535540-000000000-00000
https://www.researchgate.net/publication/225063716_Use_of_virtual_screening_for_discovering_antiretroviral_compounds_interacting_with_the_HIV-1_nucleocapsid_protein
https://www.hindawi.com/journals/ijh/2012/760706/
http://europepmc.org/abstract/med/25739648
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0158986
https://www.researchgate.net/profile/Ursula_Dietrich2/publication/225063716_Use_of_virtual_screening_for_discovering_antiretroviral_compounds_interacting_with_the_HIV-1_nucleocapsid_protein/links/54f846350cf28d6deca1438f.pdf
https://aidsinfo.nih.gov/guidelines/html/1/adult-and-adolescent-arv-guidelines/3/tests-for-initial-assessment-and-follow-up
http://uhavax.hartford.edu/bugl/treat.htm
http://www.jove.com/video/51222/high-throughput-screening-for-broad-spectrum-chemical-inhibitors-rna
https://www.elsevier.com/__data/promis_misc/jep2006_106_p290.pdf
https://jbiomedsci.biomedcentral.com/articles/10.1186/1423-0127-20-73
https://www.theseus.fi/bitstream/handle/10024/23236/Vankova%20Magdalena.pdf?sequence=1
http://www.who.int/tdr/research/ntd/dengue/dengue_full_length_report.pdf
https://en.wikipedia.org/wiki/Antiviral_drug
http://grantome.com/grant/NIH/R01-AI122301-01
Q. Ashton Acton, PhD . 2012. Virus Diseases: New Insights for the Healthcare Professional: ScholarlyEditions,,Pp.357. ISBN1464970025, 9781464970023
http://www.csir.co.za/csir_conference_2006/Khati,Makobetsa.Aptamers.Anewplatformtec.html
The University of Texas at Austin. Biochemistry . 2008.Aptamers for in Vivo Applications. ProQuest,Pp.222. ISBN0549705414, 9780549705413
http://jvi.asm.org/content/77/23/12692.full
Regards
Prof. Houda Kawas
Article Use of virtual screening for discovering antiretroviral comp...
Thank you very much for your help. I really appreciate! :)
you most welcome
Houda
My question is about Baculovirus mediated protein expression- The vector pFAST BAC 1, the carrier vector has Amp and Gentamicin resistance and Bacmid present in Bac5alpha competent cell has Tet...
02 March 2012 1,022 1 View
To express recombinant protein I need to use Baculovirus system. I am confused about the two manuals.
01 February 2012 4,873 3 View
Hello. I am working on ROS production of two systems: system A is cerium oxide and hydrogen peroxide, system B is cerium oxide nanoparticle, hydrogen peroxide and potassium bromide. I did some...
04 August 2024 5,974 3 View
Is this circle one of the rings?
03 August 2024 5,988 0 View
I want to perform a CRISPRa/i library screening for candidate regulatory factors that affect pathogenic Th17 differentiation in PBMC. But I am wondering how to define the size of gene library, so...
31 July 2024 2,150 0 View
I have been running a MAGeCK test command on the terminal for a CRISPR screen to rank sgRNAs and genes based on the read count tables. However, I get only the plot of the top-ranked genes...
28 July 2024 9,811 1 View
if you have MRS broth already prepared, what is the manner you will follow for preparing hyper-sweet medium for screening of EPS producer LAB? what the concentration of saccharose or glucose you...
26 July 2024 6,606 0 View
I have to quantify the enzymatic activities of SOD in plants using a method that employs hypoxanthine-xanthine oxidase to create O2. The colorimetric reaction was performed by combining...
23 July 2024 8,492 3 View
I have conducted virtual screening using Schrödinger on a database of 17,000 molecules. Unfortunately, I cannot use the system with the Schrödinger license at the moment. I am trying to find a way...
18 July 2024 2,881 4 View
Is there a method that I can measure alcohol dehydrogenase activity using NAD+ in enzyme extraction from plants?
17 July 2024 935 1 View
We have mice brains that were over-fixed due to old PFA used during perfusion. Thus, the synapses are no longer being labeled by the Synaptophysin (SY38) mAB. which works perfectly every other...
17 July 2024 7,767 3 View
It was assumed that 4E8 T cells should be isolated and activated using plate-bound anti-human CD3, after which would be used for a genome-wide CRISPR screen. (Ref: Genome-wide CRISPR Screens in...
17 July 2024 3,371 0 View