Is there any way to use QMS (Quadrupole Mass Spectrometer) for quantitative analysis of the gaseous stream? If so, does anybody know how to do so, or could anyone suggest an article where this procedure is explained?
You shoud study the construction of GC-MS devices, they are constructed to do exactly what you're asking for.
It is possible to abuse a standard quad device to examine the airborn species surounding the ion enterance. In your case you will need some kind of splitter to divert a portion of the gasstream towards the ms enterance. Just before the enterance (this is at atmosferic pressure ) you have to ionize the gasstream. This can be done in several way's. The easyest is the use of a corona discharge needle just before the ion enterance. An other option would be photoionization. If you have the possibility to acces the gas stream in the vacuum part electron impact ionization is within reach.
I used a Siex API III tripple quad with the corona approach with succses, the ion enterance in this device uses a curtan gas construction witch makes the positioning of the needle and the curtan gas parameters critical.
I'm sorry, but I'm not sure I have understood your answer. We use a QMS Hiden hpr 20 ( http://www.hideninc.com/gas-analysis-hpr-20.html ), which a capillary inlet for sampling gaseous source. The problem is that I'm not sure I can use it as a quantitative instrument rather than qualitative one and so I was minding if I could get any advice or maybe any kind of paper. I hope I've been clearer than in the question.
My mistake.
It should be possible. The main question will be how to create a calibration curve. I would contact Hideninc first they should know the limitations of their device.
In each case it would be advisable to incorporate some kind of internal standard to compensate for variations in the amount of gas passing trough the capillary as this is influenced by temperature, pressure drop and viscosity .
I assume the device uses EI ionization (your link is dead) . The article below discuses some of the issues involved.
https://www.researchgate.net/publication/45422738_Characterization_and_improvement_of_signal_drift_associated_with_electron_ionization_quadrupole_mass_spectrometry?ev=prf_pub
Article Characterization and Improvement of Signal Drift Associated ...
Thank you for your kind answer. I will try to ask hiden for more information about their instrument. We use an internal standard (an inert gas like He or Ar) as a reference.
(Link repaired - sorry, my mistake)
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