Do tumor cells subjected to treatments with apoptosis-inducing drugs have up-regulated oncogene expression as a "defense mechanism"?

Luis Felipe Buso Bortolotto @Luis-Buso-Bortolotto-2

30 September 2014 1 560 Report

I mean genes like BFAR, IGFR1, etc.

I had Bcl-2 down-regulation and APAF1 and Bax up-regulation. But some oncogenes were up-regulated in 6 hour-treatments. Most of themwere attenuated in 24-hour treatments.

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