Parasitosis is one of the best epidemiological topics in which neuroscientists should be very interested. For instance, the presence of certains forms of T. brucei gambiense in the choroid plexus and cerebrospinal liquid may activate the glial environment of the brain, leading to the release of pro-inflammatory cytokines and the subsequent sickness behavior in infected subjects. Playing a role in nervous-immune interactions, cytokines would somehow help building an anti-parasitic memory to avoid reinfections. I would just highlight the importance of revealing processes that underlie the bidirectional memory transfer between nervous and immune systems in case of infectious diseases.