Hello all,

I have one cross over design, two different treatment A and B and two different period including one wash out period. There is only one sequence.

The measurement is like below:

Baseline Treatment A Washout Treatment B

* * *

I want to compare trt A with B using Wilcoxson sign rank test, what about baseline? Is that necessary to compare baseline with trt A and then baseline with trt B?

or should I compare only trt A with B?

any input appreciated

Thanks,