In pathological report we often see the sentence: Clinical correlation is recommended.
Can experts let me know whether plant classifications based only on molecular studies is enough to arrive at taxonomic conclusions (like segregation of a new genus, etc) or they should be supported by morphological expressions and their clear cut differences as well?
Hello Dr. Subir Bandyopadhyay:
I am a surgical pathologist and I was to your question statement of " In pathological report we often see the sentence: Clinical correlation is recommended. " This simply means that mere examination of the pathologic material (like histology, immunohistochemistry results, etc) alone may not suffice, but must be correlated with the patient's clinical findings, chief complaint and presentation, pertinent physical examination, and other relevant ancillary tests such as biochemistry results, and imaging studies (like CT scan, MRI, etc.) if available, under the context of a "Multidisciplinary Team (MDT") approach in the evaluation and management of patients. In this perspective, a better understanding of the disease, its definitive diagnosis, and most importantly, proper and correct management and treatment is not compromised. I am not a plant expert like you are, but I should say, this applies to the same principle in the determination of the correct and proper botanical taxonomic classification of a plant specie/genus by correlating its molecular phenotype as well as morphological characteristics. Thank you for sharing your interesting inquiry.
Thanks to both of you. I was away from Calcutta; hence the delay in replying.
With best wishes and regards,
Subir.
The sentence clinical correlation is recommended”. These words signify that inadequate clinical information was provided, or that an unexpected finding on examination of the pathologic material; the should be assessed clinic and this sentence not seen in pathological investigation only, but in other investigation like MRI, CT Scan, etc...
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