Hi,

I am looking into methods to extract DNA from fish tissue. Our lab has used the glassmilk approach in the past but recently switched to using Chelex. I was wondering if anyone knew of any tradeoffs of the Chelex approach in terms of the quality of the data or depth of coverage of the sequencing? Cost is similar with both but the effort involved in the Chelex technique is less, so I would like to know if using this would still yield good sequencing down the line.