Cell lines after going through number of passage trends to change. Is there any fixed duration after which cell lines should be authenticated (by STR profiling etc)?How often one should authenticate their cell lines?
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When You Need STR Analysis?
1.Before a new research finding is submitting, or when applying for a new project.
2.When recovery cells that have frozen storage for many years.
3.When a new cell line is acquired, and when preparing a new cell bank for storage.
4.An established cell line which have grown continuously for more than 10 passages.
5.When the performance of cell line is unstable or the result is different from expected.
6.When conducting the chimerism examination after allogeneic cell transplantation.
https://www.creative-bioarray.com/Services/Short-Tandem-Repeat-Analysis.htm
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