Cross Coupling is one of the biggest areas of organic synthesis in my opinion

Carbon–hydrogen bond functionalization (C–H functionalization) and asymmetric synthesis are hot topics in organic chemistry.

Methane functionalization

Syntheses of chromenes and coumarin derivatives.

Another hot topic is combinatorial (solid and homogeneus phase) synthesis and biological evaluation of synthesized libraries..

Organic semiconductors, and C-H functionalization :)

Continuous flow reaction systems.

synthesis of novel new chemical entities [NCE] towards the challenging diseases like diabetics & cancer to provide solution to the society.

C-C bond activation, Strategies for Late-Stage Modification, Chiral Organometallics!

Semi -synthetic enzymes.

Some simple important natural product synthesis

In my opinion, organocatalysis (iminium, enamine, Bronsted/Lewis acid/base, hypervalent Iodine etc.) in synthesizing important precursors for natural products. Besides, C-H activation and cross-coupling using cheaper metal and ligand should be another field.

Preparation of nano films,preparation of bio polymers ,natural dyes are the best topics

Thank you P.E. Kumar. Yes, these are hot topics. Natural dyes can be obtained from fruits and vegetables abundantly.

Great idea, microwave assisted organic synthesis. Thank you Edward Cook.

Organic compounds based nano particles.

Preparation of pipiridones . chromones, flavones.carbazoles.

Green chemistry catalysts and its applications( like proline , bis imines ,zeolites & Heterocyclic carbenes).