Absolutely.... PRF can be obtained as a membrane which can be used in such cases along with CAF or say LDF or BF etc.. its autologous, reduced donor sit morbidity and also facilitates regeneration by delivering an intricate complex of various growth factors like VEGF, TGF, IGF, FGF etc..

Upon that it has been proved to be effective in such cases in various evidence based studies...

Sasha Jankovic et al... AR Pradeep et al, Del Corso et al.. Anil Kumar et al... and lot more.... Systematic reviews DelFabbro et al... Plackova et al. Saurav et al.... etc prove its definative efficacy in periodontal regeneration.

I have tried to use PRF for many things including replacement of connective tissue grafts. Simply put, I have found nothing better than connective tissue for root coverage. The PRF seemed to work for coronally advanced flaps or lateral pedicle flaps when the host gingival thickness is adequate. Then again, Emdogain has shown to have good effectiveness in these instances as well.

I have tried using PRF as a GBR/GTR membrane with variable success. Sometimes it worked well, sometimes it did not. Believe me, I WANTED the PRF to work. I can make a PRF membrane for $1. If it would work predictably, I could save thousands of dollars every year in my practice! Unfortunately, the results for PRF in my hands were a bit too unpredictable to continue using it on a daily basis.

Thanks to Dr Dan and Dr Saurav for your valuable ideas. Now-a-days I m trying to use PRF specially in every cases such as bone defect, recession as filler or membrane.

Let me try to get good result and it may save money from expenditure of bone graft materials and membranes.

In my 20 years of experience, I have tried many materials as a way to prevent a second surgical site, but I keep going back to the palate.  I get by far better, more predictable results using the patient's own connective tissue.