I am planning to find variation of modulus of subgrade reaction through software like FLAC 2D.
You are dealing with physical properties that could vary from one location to another. No software can accurately evaluate it. You can plot it.
I don't think you are on a good path. However if you have reasonable estimate of the stiffness of the subsoil via standard investigations you can model the problem in Flac and try to estimate a subgrade reaction.
Yes it can possible
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