The following literature may be useful for your research

This application note describes methods for determining adsorption isotherms using PreDictor 96-well filter platesa and Assist software. PreDictor filter plates are designed for screening conditions for chromatography processdevelopment, while Assist software supports multivariatedesign of experiments and evaluation of collected data interms of mass balance, adsorption isotherm estimation, and different types of plots 

Ref:Adsorption equilibrium isotherm studies using a high-throughput

method

https://www.gelifesciences.com/.../litdoc28940362AA_20110831104528...

You load solver add-in to your Microsoft Excel using the link below:

http://office.microsoft.com/en-in/excel-help/load-the-solver-add-in-HP010021570.aspx

Solver tutorial can be had from the link below:

http://www.excel-easy.com/data-analysis/solver.html

Thanks to you all for the valuable suggestions.

Hi Adejo,

As suggested in the reply by Singh, I too recommend you to use the Solver functionality in spreadsheets. In addition to Excel, you can do the same work in the spreadsheets from free open software like Libreoffice (http://www.libreoffice.org/) or Gnumeric (http://www.gnumeric.org/), for example.

In all cases, one uses Solver to optimize the values of parameters of a fitting equation such that the sum of square differences between experimental and calculated value of the function is minimal. That is, one does a least-squares fitting of the function (for example, an adsorption isotherm) to the experimental values.

A very good guide to use Solver for fitting equations to given -usually experimental- values of a quantity is given in:

Kemmer, G., & Keller, S. (2010). Nonlinear least-squares data fitting in Excel spreadsheets. Nature protocols, 5(2), 267-281.

There it is also explained a way of estimating the uncertainties of the best-fitting values of parameters.

Good luck!

Hi,

you can try the software "octave", which is an open access software. You can plot your function and change the parameters. You would get an impression how the parameters influence your equation.

Go to:

www.gnu.org/software/octave/

and have a look.

best wishes -pr

This can be solved using linear and nonlinear regression analysis. I am adding few articles that might help you. Alongside Solver tool in excel you also can use MATLAB, in which you can do it by curve fitting tool.

http://www.sciencedirect.com/science/article/pii/S0304389406004109

You can use solver option of Microsoft excel. You don't need high level of software. Please google if you don't know how to use solver option. 

Use Matlab (fmincon function) or Aspen Custom Modeler (Estimation tool). In Excell you can use its solver option.

Hy

You can use an simple spread sheat, using regression analisys.

Or if you prefer you can deal with Grafit from erithacus software or with Pro Fit from quanta software.

I cherish you all for this lively discussion. Much thanks.

Dear Sylvester,

Please verify the correctness of your equation. I think that the term 1/qm is missing in the second term on the right side of proposed equation - if  Langmuir adsorption isotherm was used to fit the experimental data. 

you could simply get the parameters using Excel from Langmuir's equation.

You can use Excel solver or origin in addition several other software, for example, Polmath, Matlab etc.

MATLAB, Polymath or even MS Excel can solve this equation perfectly well,

The equation is a new isotherm we are trying out pls, not Langmuir- Bercic. Thanks.

You can use "table curve 2D".

http://www.sigmaplot.com/products/tablecurve2d/tablecurve2d.php

It's easy to use. You can give any form of the equation with unlimited number of parameters then estimate them.

Could you show us raw experimental data?

Bercic, please we are trying to see whether something good can come from the equation.You can generate data and try it. It cannot stand here to get you data.

There is something  similar called Adejo-Ekwenchi  isotherm which I formulated and tested and it has not only been published but has been used with other results. You may wish to see our publications under my page within this community.

Thanks